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The small sample sizes and high attrition rates (dropping from 51 in month 3 to 24 by month 6 in sample 2) make the results of longitudinal trajectory analyses exploratory as statistical power to detect effects is limited

Future work could utilise this approach to examine atomic-level binding interactions and receptor engagement of existing triple-agonist therapies

A person with a BMI of 24 and fasting glucose above 125 mg/dL qualifies for treatment based on diabetes status alone, not weight criteria

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